Effect of heparin and low-molecular weight heparin on serum potassium and sodium levels
نویسندگان
چکیده
منابع مشابه
Effect of switching unfractionated heparin to low-molecular-weight heparin on serum potassium in hemodialysis patients.
INTRODUCTION Unfractionated (UF) heparin is the most common anticoagulant used during hemodialysis. Failure of the kidneys to excrete potassium as well as heparin-induced reduction of aldosterone synthesis put hemodialysis patients at risk of hyperkalemia. It has not yet been clearly known whether hyperkalemia is also induced by low-molecular-weight (LMW) heparins. This study aimed to evaluate ...
متن کاملEffect of low-molecular-weight heparin on potassium homeostasis.
BACKGROUND Low-molecular-weight heparins (LMWHs) are being preferred to unfractionated heparin (UFH) because of their superior convenience and a comparable or slightly better toxicity profile. Whether LMWH has an inhibitory effect on aldosterone that causes hyperkalemia is yet uncertain. METHODS Twenty-eight patients (all male; mean age: 70 years, range 52-87 years) placed on LMWH therapy (40...
متن کاملHeparin and low-molecular-weight heparin.
Heparin is one of the oldest biological medicines, and has an established place in the prevention and treatment of venous thrombosis. Low-molecular-weight heparins (LMWH) have been developed by several manufacturers and have advantages in terms of pharmacokinetics and convenience of administration. They have been shown to be at least as effective and safe as unfractionated heparin and have repl...
متن کاملLow Molecular Weight Heparin Overdose: A 10 Year Case Series
Background: Low molecular weight heparin (LMWH) is used for the treatment and prevention of coagulative disorders. Few patients receiving therapeutic doses of LMWH develop major hemorrhage. Currently there are few reports in the literature on acute overdose on adults. In this study, clinical profile, treatment and outcome of 21 patients who acutely overdosed enoxaparin are described. Method...
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Low molecular weight heparin-modified isoliquiritigenin-loaded solid lipid nanoparticle (LMWH-ISL-SLN) was developed for injective application. The morphological observation, particle diameter and zeta potential of LMWH-ISL-SLN were characterized using transmission electron microscopy (TEM) and a Malvern Zetasizer. Its entrapment efficiency (EE) and drug loading (DL) were determined by ultracen...
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ژورنال
عنوان ژورنال: Journal of Pharmacology and Pharmacotherapeutics
سال: 2011
ISSN: 0976-500X
DOI: 10.4103/0976-500x.85956